Mouse Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 Alpha, PGC1A ELISA Kit , 96T Cell Screening and Imaging PubMed: 20364087

PubMed: 20364087

Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia

MIM 153240) (summary by Weinreich et al

via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity)

and its expression has been shown to be induced by wildtype p53

Mouse Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 Alpha, PGC1A ELISA Kit , 96T Cell Screening and Imaging PubMed: 20364087Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in